UBE2L6

GENE INFORMATION

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Gene name

UBE2L6 (HGNC Symbol)

Synonyms

UBCH8

Description

Ubiquitin-conjugating enzyme E2L 6 (HGNC Symbol)

Entrez gene summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]

Chromosome

11

Cytoband

q12.1

Chromosome location (bp)

57551656 - 57568284

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156587 (version 78.38)

Entrez gene

9246

UniProt

O14933 (UniProt - Evidence at protein level)

neXtProt

NX_O14933

Antibodypedia

UBE2L6 antibodies
 

PROTEIN VIEW

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UBE2L6-001
 
UBE2L6-002
 
UBE2L6-004
 
UBE2L6-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBE2L6-001 ENSP00000287156
ENST00000287156
O14933
Show all »
Show » Show » 153 17.8 No 0
UBE2L6-002 ENSP00000341980
ENST00000340573
O14933
Show all »
Show » Show » 87 10.1 No 0
UBE2L6-004 ENSP00000435265
ENST00000527022
E9PKW8
Show all »
Show » 65 7.5 No 0
UBE2L6-005 ENSP00000434348
ENST00000526659
E9PQT7
Show all »
Show » Show » 127 15 No 0