STEAP2

GENE INFORMATION

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Gene name

STEAP2 (HGNC Symbol)

Synonyms

IPCA-1, PCANAP1, STAMP1, STMP

Description

STEAP family member 2, metalloreductase (HGNC Symbol)

Entrez gene summary

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q21.13

Chromosome location (bp)

90167590 - 90238137

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000157214 (version 78.38)

Entrez gene

261729

UniProt

Q8NFT2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NFT2

Antibodypedia

STEAP2 antibodies
 

PROTEIN VIEW

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STEAP2-001
 
STEAP2-002
 
STEAP2-003
 
STEAP2-004
 
STEAP2-006
 
STEAP2-007
 
STEAP2-009
 
STEAP2-010
 
STEAP2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STEAP2-001 ENSP00000287908
ENST00000287908
Q8NFT2
Show all »
Show » Show » 490 56.1 No 6
STEAP2-002 ENSP00000378123
ENST00000394626
Q8NFT2
Show all »
Show » Show » 454 52.1 No 6
STEAP2-003 ENSP00000378128
ENST00000394632
Q8NFT2
Show all »
Show » Show » 419 47.9 No 4
STEAP2-004 ENSP00000378120
ENST00000394622
Q8NFT2
Show all »
Show » Show » 490 56.1 No 6
STEAP2-006 ENSP00000378125
ENST00000394629
Q8NFT2
Show all »
Show » Show » 454 52.1 No 6
STEAP2-007 ENSP00000415931
ENST00000426158
C9JHX5
Show all »
Show » 88 9.6 No 0
STEAP2-009 ENSP00000401783
ENST00000428074
C9JLP2
Show all »
Show » Show » 182 20.3 No 0
STEAP2-010 ENSP00000384191
ENST00000402625
B5MC02
Show all »
Show » Show » 403 46 No 4
STEAP2-201 ENSP00000378119
ENST00000394621
Q8NFT2
Show all »
Show » Show » 490 56.1 No 6