NCF1

GENE INFORMATION

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Gene name

NCF1 (HGNC Symbol)

Synonyms

NCF1A, NOXO2, p47phox, SH3PXD1A

Description

Neutrophil cytosolic factor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q11.23

Chromosome location (bp)

74773962 - 74789315

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158517 (version 78.38)

Entrez gene

653361

UniProt

P14598 (UniProt - Evidence at protein level)

neXtProt

NX_P14598

Antibodypedia

NCF1 antibodies
 

PROTEIN VIEW

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NCF1-001
 
NCF1-011
 
NCF1-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NCF1-001 ENSP00000289473
ENST00000289473
P14598
Show all »
Show » Show » 390 44.7 No 0
NCF1-011 ENSP00000401935
ENST00000442021
Show » Show » 146 17.1 No 0
NCF1-014 ENSP00000392870
ENST00000433458
Show » Show » 163 19.3 No 0