NBL1

GENE INFORMATION

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Gene name

NBL1 (HGNC Symbol)

Synonyms

D1S1733E, DAN, DAND1, NB, NO3

Description

Neuroblastoma 1, DAN family BMP antagonist (HGNC Symbol)

Entrez gene summary

This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

19640554 - 19658456

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158747 (version 78.38)

Entrez gene

4681

UniProt

P41271 (UniProt - Evidence at protein level)

neXtProt

NX_P41271

Antibodypedia

NBL1 antibodies
 

PROTEIN VIEW

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NBL1-001
 
NBL1-002
 
NBL1-003
 
NBL1-004
 
NBL1-005
 
NBL1-006
 
NBL1-007
 
NBL1-008
 
NBL1-201
 
NBL1-202
 
NBL1-203
 
NBL1-204
 
NBL1-205
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NBL1-001 ENSP00000364278
ENST00000375136
P41271
Show all »
Show » Show » 181 19.4 Yes 0
NBL1-002 ENSP00000289749
ENST00000289749
P41271
Show all »
Show » Show » 216 23.2 No 0
NBL1-003 ENSP00000390607
ENST00000451758
A3KFI5
Show all »
Show » 128 13.9 Yes 0
NBL1-004 ENSP00000412419
ENST00000428975
A3KFI4
Show all »
Show » 117 12.8 Yes 0
NBL1-005 ENSP00000399333
ENST00000439664
A3KFI2
Show all »
Show » 109 11.9 Yes 0
NBL1-006 ENSP00000400250
ENST00000425400
A3KFI3
Show all »
Show » 116 12.7 Yes 0
NBL1-007 ENSP00000391858
ENST00000439278
A3KFI1
Show all »
Show » 128 14 No 0
NBL1-008 ENSP00000394079
ENST00000427894
E5RFZ1
Show all »
Show » 163 17.5 Yes 0
NBL1-201 ENSP00000449007
ENST00000548815
P41271
Show all »
Show » Show » 181 19.4 Yes 0
NBL1-202 ENSP00000478223
ENST00000615215
E5RFZ1
Show all »
Show » Show » 215 23.2 No 0
NBL1-203 ENSP00000483061
ENST00000618761
P41271
Show all »
Show » Show » 181 19.4 Yes 0
NBL1-204 ENSP00000478885
ENST00000621723
P41271
Show all »
Show » Show » 181 19.4 Yes 0
NBL1-205 ENSP00000480391
ENST00000622566
P41271
Show all »
Show » Show » 181 19.4 Yes 0