HTR6

GENE INFORMATION

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Gene name

HTR6 (HGNC Symbol)

Synonyms

5-HT6, 5-HT6R

Description

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

19665287 - 19679562

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158748 (version 78.38)

Entrez gene

3362

UniProt

P50406 (UniProt - Evidence at protein level)

neXtProt

NX_P50406

Antibodypedia

HTR6 antibodies
 

PROTEIN VIEW

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HTR6-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HTR6-001 ENSP00000289753
ENST00000289753
P50406
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