UROC1

GENE INFORMATION

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Gene name

UROC1 (HGNC Symbol)

Synonyms

FLJ31300, HMFN0320

Description

Urocanate hydratase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Chromosome

3

Cytoband

q21.3

Chromosome location (bp)

126481281 - 126517773

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159650 (version 78.38)

Entrez gene

131669

UniProt

Q96N76 (UniProt - Evidence at protein level)

neXtProt

NX_Q96N76

Antibodypedia

UROC1 antibodies
 

PROTEIN VIEW

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UROC1-001
 
UROC1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UROC1-001 ENSP00000290868
ENST00000290868
Q96N76
Show all »
Show » Show » 676 74.8 No 0
UROC1-002 ENSP00000373073
ENST00000383579
Q96N76
Show all »
Show » Show » 736 80.9 No 0