ATP6V0D1

GENE INFORMATION

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Gene name

ATP6V0D1 (HGNC Symbol)

Synonyms

ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD

Description

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

67438014 - 67481237

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159720 (version 78.38)

Entrez gene

9114

UniProt

P61421 (UniProt - Evidence at protein level)

neXtProt

NX_P61421

Antibodypedia

ATP6V0D1 antibodies
 

PROTEIN VIEW

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ATP6V0D1-001
 
ATP6V0D1-002
 
ATP6V0D1-015
 
ATP6V0D1-017
 
ATP6V0D1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V0D1-001 ENSP00000290949
ENST00000290949
P61421
Show all »
Show » Show » 351 40.3 No 0
ATP6V0D1-002 ENSP00000441282
ENST00000540149
F5GYQ1
Show all »
Show » Show » 392 44.7 No 0
ATP6V0D1-015 ENSP00000463328
ENST00000565835
Show » 232 26.7 No 0
ATP6V0D1-017 ENSP00000455802
ENST00000564615
Show » 227 25.5 No 0
ATP6V0D1-201 ENSP00000473515
ENST00000602876
R4GN72
Show all »
Show » Show » 274 31.7 No 0