U2AF1

GENE INFORMATION

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Gene name

U2AF1 (HGNC Symbol)

Synonyms

RN, RNU2AF1, U2AF35, U2AFBP

Description

U2 small nuclear RNA auxiliary factor 1 (HGNC Symbol)

Entrez gene summary

This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.3

Chromosome location (bp)

43092956 - 43107587

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160201 (version 78.38)

Entrez gene

7307

UniProt

Q01081 (UniProt - Evidence at protein level)

neXtProt

NX_Q01081

Antibodypedia

U2AF1 antibodies
 

PROTEIN VIEW

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U2AF1-001
 
U2AF1-002
 
U2AF1-004
 
U2AF1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

U2AF1-001 ENSP00000291552
ENST00000291552
Q01081
Show all »
Show » Show » 240 27.9 No 0
U2AF1-002 ENSP00000369629
ENST00000380276
Q01081
Show all »
Show » Show » 240 27.9 No 0
U2AF1-004 ENSP00000418705
ENST00000459639
Q01081
Show all »
Show » Show » 167 19.7 No 0
U2AF1-201 ENSP00000381205
ENST00000398137
Q01081
Show all »
Show » Show » 167 19.7 No 0