FCRL3

GENE INFORMATION

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Gene name

FCRL3 (HGNC Symbol)

Synonyms

CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e

Description

Fc receptor-like 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q23.1

Chromosome location (bp)

157674321 - 157700857

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160856 (version 78.38)

Entrez gene

115352

UniProt

Q96P31 (UniProt - Evidence at protein level)

neXtProt

NX_Q96P31

Antibodypedia

FCRL3 antibodies
 

PROTEIN VIEW

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FCRL3-004
 
FCRL3-006
 
FCRL3-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCRL3-004 ENSP00000357169
ENST00000368186
Q96P31
Show all »
Show » Show » 742 81.9 Yes 1
FCRL3-006 ENSP00000357167
ENST00000368184
Q96P31
Show all »
Show » Show » 734 80.9 Yes 1
FCRL3-011 ENSP00000473680
ENST00000496769
R4GNJ6
Show all »
Show » Show » 256 29 Yes 0