SRSF2

GENE INFORMATION

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Gene name

SRSF2 (HGNC Symbol)

Synonyms

PR264, SC-35, SC35, SFRS2, SFRS2A

Description

Serine/arginine-rich splicing factor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

76734115 - 76737374

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161547 (version 78.38)

Entrez gene

6427

UniProt

Q01130 (UniProt - Evidence at protein level)

neXtProt

NX_Q01130

Antibodypedia

SRSF2 antibodies
 

PROTEIN VIEW

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SRSF2-001
 
SRSF2-002
 
SRSF2-003
 
SRSF2-007
 
SRSF2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRSF2-001 ENSP00000353089
ENST00000359995
Q01130
Show all »
Show » Show » 221 25.5 No 0
SRSF2-002 ENSP00000441780
ENST00000508921
Q01130
Show all »
Show » Show » 209 24.2 No 0
SRSF2-003 ENSP00000376276
ENST00000392485
Q01130
Show all »
Show » Show » 221 25.5 No 0
SRSF2-007 ENSP00000350877
ENST00000358156
J3KP15
Show all »
Show » Show » 134 15.5 No 0
SRSF2-008 ENSP00000463317
ENST00000583836
J3QL05
Show all »
Show » Show » 130 15.2 No 0