ITGA5

GENE INFORMATION

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Gene name

ITGA5 (HGNC Symbol)

Synonyms

CD49e, FNRA

Description

Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

54395261 - 54419460

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161638 (version 78.38)

Entrez gene

3678

UniProt

P08648 (UniProt - Evidence at protein level)

neXtProt

NX_P08648

Antibodypedia

ITGA5 antibodies
 

PROTEIN VIEW

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ITGA5-001
 
ITGA5-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITGA5-001 ENSP00000293379
ENST00000293379
P08648
Show all »
Show » Show » 1049 114.5 Yes 1
ITGA5-012 ENSP00000450267
ENST00000547197
Show » 119 13.2 No 1