SSTR5

GENE INFORMATION

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Gene name

SSTR5

Synonyms

Description

Somatostatin receptor 5 (HGNC Symbol)

Entrez gene summary

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

1078781 - 1080142

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162009 (version 78.38)

Entrez gene

6755

UniProt

P35346 (UniProt - Evidence at protein level)

neXtProt

NX_P35346

Antibodypedia

SSTR5 antibodies
 

PROTEIN VIEW

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SSTR5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SSTR5-001 ENSP00000293897
ENST00000293897
P35346
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