USP1

GENE INFORMATION

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Gene name

USP1

Synonyms

Description

Ubiquitin specific peptidase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p31.3

Chromosome location (bp)

62436297 - 62451804

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162607 (version 78.38)

Entrez gene

7398

UniProt

O94782 (UniProt - Evidence at protein level)

neXtProt

NX_O94782

Antibodypedia

USP1 antibodies
 

PROTEIN VIEW

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USP1-001
 
USP1-002
 
USP1-003
 
USP1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

USP1-001 ENSP00000343526
ENST00000339950
O94782
Show all »
Show » Show » 785 88.2 No 0
USP1-002 ENSP00000403662
ENST00000452143
C9JC88
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Show » Show » 186 20.9 No 0
USP1-003 ENSP00000387986
ENST00000442679
C9JWX4
Show all »
Show » 87 9.7 No 0
USP1-201 ENSP00000360188
ENST00000371146
O94782
Show all »
Show » Show » 785 88.2 No 0