LHX8

GENE INFORMATION

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Gene name

LHX8 (HGNC Symbol)

Synonyms

Lhx7

Description

LIM homeobox 8 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

1

Cytoband

p31.1

Chromosome location (bp)

75128434 - 75161533

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000162624 (version 78.38)

Entrez gene

431707

UniProt

Q68G74 (UniProt - Evidence at transcript level)

neXtProt

NX_Q68G74

Antibodypedia

LHX8 antibodies
 

PROTEIN VIEW

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LHX8-001
 
LHX8-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LHX8-001 ENSP00000294638
ENST00000294638
Q68G74
Show all »
Show » Show » 356 39.3 No 0
LHX8-002 ENSP00000348597
ENST00000356261
Q68G74
Show all »
Show » Show » 346 38.2 No 0