FCGR3B

GENE INFORMATION

? »

Gene name

FCGR3B (HGNC Symbol)

Synonyms

CD16, CD16b, FCG3, FCGR3

Description

Fc fragment of IgG, low affinity IIIb, receptor (CD16b) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

161623196 - 161631963

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162747 (version 78.38)

Entrez gene

2215

UniProt

O75015 (UniProt - Evidence at protein level)

neXtProt

NX_O75015

Antibodypedia

FCGR3B antibodies
 

PROTEIN VIEW

? »
 
 
 
FCGR3B-001
 
FCGR3B-002
 
FCGR3B-003
 
FCGR3B-005
 
FCGR3B-201
 
FCGR3B-202
 
FCGR3B-203
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCGR3B-001 ENSP00000433642
ENST00000531221
M9MML6
Show all »
Show » Show » 269 29.9 No 1
FCGR3B-002 ENSP00000394204
ENST00000421702
Show » Show » 254 28.2 No 1
FCGR3B-003 ENSP00000356941
ENST00000367964
O75015
Show all »
Show » Show » 233 26.2 Yes 1
FCGR3B-005 ENSP00000437084
ENST00000534776
E9PNY5
Show all »
Show » Show » 104 11.9 No 0
FCGR3B-201 ENSP00000294800
ENST00000294800
O75015
Show all »
Show » Show » 233 26.2 Yes 1
FCGR3B-202 ENSP00000482838
ENST00000613418
E9PNY5
Show all »
Show » Show » 216 24.4 No 1
FCGR3B-203 ENSP00000478466
ENST00000614870
Show » Show » 130 14.4 No 1