CTSS

GENE INFORMATION

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Gene name

CTSS

Synonyms

Description

Cathepsin S (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

150730196 - 150765957

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163131 (version 78.38)

Entrez gene

1520

UniProt

P25774 (UniProt - Evidence at protein level)

neXtProt

NX_P25774

Antibodypedia

CTSS antibodies
 

PROTEIN VIEW

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CTSS-001
 
CTSS-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTSS-001 ENSP00000357981
ENST00000368985
P25774
Show all »
Show » Show » 331 37.5 Yes 0
CTSS-006 ENSP00000408414
ENST00000448301
P25774
Show all »
Show » Show » 281 31.6 Yes 0