PROK2

GENE INFORMATION

? »

Gene name

PROK2 (HGNC Symbol)

Synonyms

BV8, KAL4, MIT1, PK2

Description

Prokineticin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p13

Chromosome location (bp)

71771656 - 71785206

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163421 (version 78.38)

Entrez gene

60675

UniProt

Q9HC23 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HC23

Antibodypedia

PROK2 antibodies
 

PROTEIN VIEW

? »
 
 
 
PROK2-001
 
PROK2-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PROK2-001 ENSP00000295618
ENST00000353065
Q9HC23
Show all »
Show » Show » 108 11.7 Yes 0
PROK2-002 ENSP00000295619
ENST00000295619
Q9HC23
Show all »
Show » Show » 129 14.3 Yes 0