FEV

GENE INFORMATION

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Gene name

FEV (HGNC Symbol)

Synonyms

Pet-1

Description

FEV (ETS oncogene family) (HGNC Symbol)

Entrez gene summary

This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q35

Chromosome location (bp)

218981087 - 218985657

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163497 (version 78.38)

Entrez gene

54738

UniProt

Q99581 (UniProt - Evidence at protein level)

neXtProt

NX_Q99581

Antibodypedia

FEV antibodies
 

PROTEIN VIEW

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FEV-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FEV-001 ENSP00000295727
ENST00000295727
Q99581
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