GMPS

GENE INFORMATION

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Gene name

GMPS

Synonyms

Description

Guanine monphosphate synthase (HGNC Symbol)

Entrez gene summary

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q25.31

Chromosome location (bp)

155870536 - 155944026

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163655 (version 78.38)

Entrez gene

8833

UniProt

P49915 (UniProt - Evidence at protein level)

neXtProt

NX_P49915

Antibodypedia

GMPS antibodies
 

PROTEIN VIEW

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GMPS-001
 
GMPS-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GMPS-001 ENSP00000419851
ENST00000496455
P49915
Show all »
Show » Show » 693 76.7 No 0
GMPS-002 ENSP00000295920
ENST00000295920
P49915
Show all »
Show » Show » 594 65.9 No 0