PF4

GENE INFORMATION

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Gene name

PF4 (HGNC Symbol)

Synonyms

CXCL4, SCYB4

Description

Platelet factor 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

73981077 - 73982124

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163737 (version 78.38)

Entrez gene

5196

UniProt

P02776 (UniProt - Evidence at protein level)

neXtProt

NX_P02776

Antibodypedia

PF4 antibodies
 

PROTEIN VIEW

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PF4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PF4-001 ENSP00000296029
ENST00000296029
P02776
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