TOPBP1

GENE INFORMATION

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Gene name

TOPBP1 (HGNC Symbol)

Synonyms

KIAA0259, TOP2BP1

Description

Topoisomerase (DNA) II binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q22.1

Chromosome location (bp)

133598175 - 133661893

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163781 (version 78.38)

Entrez gene

11073

UniProt

Q92547 (UniProt - Evidence at protein level)

neXtProt

NX_Q92547

Antibodypedia

TOPBP1 antibodies
 

PROTEIN VIEW

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TOPBP1-001
 
TOPBP1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TOPBP1-001 ENSP00000260810
ENST00000260810
Q92547
Show all »
Show » Show » 1522 170.7 No 0
TOPBP1-003 ENSP00000421179
ENST00000508524
Show » 206 23.3 No 0