AIMP1

GENE INFORMATION

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Gene name

AIMP1 (HGNC Symbol)

Synonyms

EMAP-2, EMAPII, p43, SCYE1

Description

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]

Chromosome

4

Cytoband

q24

Chromosome location (bp)

106315544 - 106349226

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164022 (version 78.38)

Entrez gene

9255

UniProt

Q12904 (UniProt - Evidence at protein level)

neXtProt

NX_Q12904

Antibodypedia

AIMP1 antibodies
 

PROTEIN VIEW

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AIMP1-001
 
AIMP1-002
 
AIMP1-004
 
AIMP1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AIMP1-001 ENSP00000378191
ENST00000394701
Q12904
Show all »
Show » Show » 336 37 No 0
AIMP1-002 ENSP00000350699
ENST00000358008
Q12904
Show all »
Show » Show » 312 34.4 No 0
AIMP1-004 ENSP00000423681
ENST00000510207
D6R937
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Show » Show » 150 16.6 No 0
AIMP1-201 ENSP00000405248
ENST00000442366
Q12904
Show all »
Show » Show » 312 34.4 No 0