DEFB1

GENE INFORMATION

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Gene name

DEFB1 (HGNC Symbol)

Synonyms

BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822

Description

Defensin, beta 1 (HGNC Symbol)

Entrez gene summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

6870575 - 6878022

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164825 (version 78.38)

Entrez gene

1672

UniProt

P60022 (UniProt - Evidence at protein level)

neXtProt

NX_P60022

Antibodypedia

DEFB1 antibodies
 

PROTEIN VIEW

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DEFB1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB1-001 ENSP00000297439
ENST00000297439
P60022
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