COX6C

GENE INFORMATION

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Gene name

COX6C

Synonyms

Description

Cytochrome c oxidase subunit VIc (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]

Chromosome

8

Cytoband

q22.2

Chromosome location (bp)

99873200 - 99894062

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164919 (version 78.38)

Entrez gene

1345

UniProt

P09669 (UniProt - Evidence at protein level)

neXtProt

NX_P09669

Antibodypedia

COX6C antibodies
 

PROTEIN VIEW

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COX6C-001
 
COX6C-002
 
COX6C-003
 
COX6C-004
 
COX6C-005
 
COX6C-006
 
COX6C-007
 
COX6C-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX6C-001 ENSP00000428895
ENST00000520468
P09669
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Show » Show » 75 8.8 No 1
COX6C-002 ENSP00000429755
ENST00000518171
P09669
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Show » Show » 75 8.8 No 1
COX6C-003 ENSP00000297564
ENST00000297564
P09669
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Show » Show » 75 8.8 No 1
COX6C-004 ENSP00000429707
ENST00000523016
P09669
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Show » Show » 75 8.8 No 1
COX6C-005 ENSP00000429714
ENST00000517682
P09669
Show all »
Show » Show » 75 8.8 No 1
COX6C-006 ENSP00000428965
ENST00000522940
P09669
Show all »
Show » Show » 75 8.8 No 1
COX6C-007 ENSP00000428150
ENST00000520271
P09669
Show all »
Show » Show » 75 8.8 No 1
COX6C-008 ENSP00000429410
ENST00000524245
P09669
Show all »
Show » Show » 75 8.8 No 1