NUDT5

GENE INFORMATION

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Gene name

NUDT5 (HGNC Symbol)

Synonyms

hYSAH1, YSA1H

Description

Nudix (nucleoside diphosphate linked moiety X)-type motif 5 (HGNC Symbol)

Entrez gene summary

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

12165325 - 12196144

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165609 (version 78.38)

Entrez gene

11164

UniProt

Q9UKK9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKK9

Antibodypedia

NUDT5 antibodies
 

PROTEIN VIEW

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NUDT5-001
 
NUDT5-002
 
NUDT5-003
 
NUDT5-004
 
NUDT5-006
 
NUDT5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NUDT5-001 ENSP00000419628
ENST00000491614
Q9UKK9
Show all »
Show » Show » 219 24.3 No 0
NUDT5-002 ENSP00000368209
ENST00000378927
A6NCQ0
Show all »
Show » Show » 180 20 No 0
NUDT5-003 ENSP00000368219
ENST00000378937
A6NFX8
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Show » Show » 232 25.9 No 0
NUDT5-004 ENSP00000407856
ENST00000444732
C9JYY9
Show all »
Show » Show » 98 11.3 No 0
NUDT5-006 ENSP00000368222
ENST00000378940
A6NJU6
Show all »
Show » Show » 186 20.6 No 0
NUDT5-201 ENSP00000445116
ENST00000537776
Q9UKK9
Show all »
Show » Show » 219 24.3 No 0