PRPF18

GENE INFORMATION

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Gene name

PRPF18 (HGNC Symbol)

Synonyms

hPrp18

Description

Pre-mRNA processing factor 18 (HGNC Symbol)

Entrez gene summary

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p13

Chromosome location (bp)

13586927 - 13630868

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165630 (version 78.38)

Entrez gene

8559

UniProt

Q99633 (UniProt - Evidence at protein level)

neXtProt

NX_Q99633

Antibodypedia

PRPF18 antibodies
 

PROTEIN VIEW

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PRPF18-001
 
PRPF18-002
 
PRPF18-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRPF18-001 ENSP00000367835
ENST00000378572
Q99633
Show all »
Show » Show » 342 39.9 No 0
PRPF18-002 ENSP00000367824
ENST00000320054
Q5T9P8
Show all »
Show » Show » 167 19.4 No 0
PRPF18-003 ENSP00000392142
ENST00000417658
Q5T9P7
Show all »
Show » Show » 249 28.9 No 0