TAF10

GENE INFORMATION

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Gene name

TAF10 (HGNC Symbol)

Synonyms

TAF2A, TAF2H, TAFII30

Description

TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa (HGNC Symbol)

Entrez gene summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.4

Chromosome location (bp)

6606296 - 6612667

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166337 (version 78.38)

Entrez gene

6881

UniProt

Q12962 (UniProt - Evidence at protein level)

neXtProt

NX_Q12962

Antibodypedia

TAF10 antibodies
 

PROTEIN VIEW

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TAF10-001
 
TAF10-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAF10-001 ENSP00000299424
ENST00000299424
Q12962
Show all »
Show » Show » 218 21.7 No 0
TAF10-004 ENSP00000480402
ENST00000527248
Show » Show » 115 12.2 No 0