SERPINB7

GENE INFORMATION

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Gene name

SERPINB7 (HGNC Symbol)

Synonyms

MEGSIN

Description

Serpin peptidase inhibitor, clade B (ovalbumin), member 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Chromosome

18

Cytoband

q21.33

Chromosome location (bp)

63752935 - 63805376

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166396 (version 78.38)

Entrez gene

8710

UniProt

O75635 (UniProt - Evidence at protein level)

neXtProt

NX_O75635

Antibodypedia

SERPINB7 antibodies
 

PROTEIN VIEW

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SERPINB7-001
 
SERPINB7-002
 
SERPINB7-004
 
SERPINB7-005
 
SERPINB7-201
 
SERPINB7-202
 
SERPINB7-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINB7-001 ENSP00000381101
ENST00000398019
O75635
Show all »
Show » Show » 380 42.9 No 0
SERPINB7-002 ENSP00000397301
ENST00000425392
C9JZR8
Show all »
Show » Show » 128 14.1 No 0
SERPINB7-004 ENSP00000402362
ENST00000447428
C9JM00
Show all »
Show » Show » 165 18.3 No 0
SERPINB7-005 ENSP00000393947
ENST00000431370
C9JZR8
Show all »
Show » Show » 128 14.1 No 0
SERPINB7-201 ENSP00000337212
ENST00000336429
O75635
Show all »
Show » Show » 380 42.9 No 0
SERPINB7-202 ENSP00000444572
ENST00000540675
O75635
Show all »
Show » Show » 363 41.2 No 0
SERPINB7-203 ENSP00000444861
ENST00000546027
O75635
Show all »
Show » Show » 380 42.9 No 0