CLEC4E

GENE INFORMATION

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Gene name

CLEC4E (HGNC Symbol)

Synonyms

CLECSF9, mincle

Description

C-type lectin domain family 4, member E (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

8533305 - 8540963

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166523 (version 78.38)

Entrez gene

26253

UniProt

Q9ULY5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULY5

Antibodypedia

CLEC4E antibodies
 

PROTEIN VIEW

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CLEC4E-001
 
CLEC4E-004
 
CLEC4E-005
 
CLEC4E-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLEC4E-001 ENSP00000299663
ENST00000299663
Q9ULY5
Show all »
Show » Show » 219 25.1 No 1
CLEC4E-004 ENSP00000387737
ENST00000446457
F8WFA1
Show all »
Show » 92 10.5 No 1
CLEC4E-005 ENSP00000443034
ENST00000545274
F5H5X7
Show all »
Show » Show » 174 20 No 0
CLEC4E-006 ENSP00000443328
ENST00000537698
Show » 94 10.5 No 0