CDH16

GENE INFORMATION

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Gene name

CDH16

Synonyms

Description

Cadherin 16, KSP-cadherin (HGNC Symbol)

Entrez gene summary

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

66908122 - 66918984

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166589 (version 78.38)

Entrez gene

1014

UniProt

O75309 (UniProt - Evidence at protein level)

neXtProt

NX_O75309

Antibodypedia

CDH16 antibodies
 

PROTEIN VIEW

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CDH16-001
 
CDH16-002
 
CDH16-004
 
CDH16-006
 
CDH16-007
 
CDH16-008
 
CDH16-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH16-001 ENSP00000299752
ENST00000299752
O75309
Show all »
Show » Show » 829 89.9 Yes 1
CDH16-002 ENSP00000377619
ENST00000394055
O75309
Show all »
Show » Show » 807 87.6 Yes 1
CDH16-004 ENSP00000455263
ENST00000568632
O75309
Show all »
Show » Show » 732 79.2 Yes 1
CDH16-006 ENSP00000454784
ENST00000565796
O75309
Show all »
Show » Show » 790 85.8 Yes 1
CDH16-007 ENSP00000456690
ENST00000570262
H3BSG2
Show all »
Show » Show » 749 81.3 Yes 1
CDH16-008 ENSP00000463451
ENST00000565235
J3QLA1
Show all »
Show » Show » 124 13.9 No 0
CDH16-009 ENSP00000460891
ENST00000567009
I3L418
Show all »
Show » Show » 238 26.4 No 0