PSCA

GENE INFORMATION

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Gene name

PSCA

Synonyms

Description

Prostate stem cell antigen (HGNC Symbol)

Entrez gene summary

This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

142670308 - 142682724

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167653 (version 78.38)

Entrez gene

8000

UniProt

O43653 (UniProt - Evidence at protein level)

neXtProt

NX_O43653

Antibodypedia

PSCA antibodies
 

PROTEIN VIEW

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PSCA-001
 
PSCA-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSCA-001 ENSP00000301258
ENST00000301258
O43653
Show all »
Show » Show » 114 12 No 1
PSCA-002 ENSP00000426508
ENST00000513264
H0YAA6
Show all »
Show » 54 6 No 0