HIST3H3

GENE INFORMATION

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Gene name

HIST3H3 (HGNC Symbol)

Synonyms

H3.4, H3/g, H3FT, H3t

Description

Histone cluster 3, H3 (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q42.13

Chromosome location (bp)

228424845 - 228425325

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168148 (version 78.38)

Entrez gene

8290

UniProt

Q16695 (UniProt - Evidence at protein level)

neXtProt

NX_Q16695

Antibodypedia

HIST3H3 antibodies
 

PROTEIN VIEW

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HIST3H3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST3H3-001 ENSP00000355657
ENST00000366696
Q16695
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