POLR2J3

GENE INFORMATION

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Gene name

POLR2J3

Synonyms

Description

Polymerase (RNA) II (DNA directed) polypeptide J3 (HGNC Symbol)

Entrez gene summary

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

102537918 - 102572656

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168255 (version 78.38)

Entrez gene

548644

UniProt

neXtProt

Antibodypedia

POLR2J3 antibodies
 

PROTEIN VIEW

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POLR2J3-005
 
POLR2J3-010
 
POLR2J3-012
 
POLR2J3-201
 
POLR2J3-202
 
POLR2J3-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POLR2J3-005 ENSP00000422109
ENST00000511313
E7EP90
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Show » Show » 76 8.4 No 0
POLR2J3-010 ENSP00000421085
ENST00000513506
E7EWC6
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Show » Show » 274 30.4 No 0
POLR2J3-012 ENSP00000421950
ENST00000513438
D6RAG0
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Show » Show » 73 8 No 0
POLR2J3-201 ENSP00000368662
ENST00000379357
T2F9S8
Show all »
Show » Show » 263 28.4 Yes 1
POLR2J3-202 ENSP00000482932
ENST00000613744
E2QRJ6
Show all »
Show » Show » 158 17.2 No 0
POLR2J3-203 ENSP00000483328
ENST00000621093
Show » Show » 115 13.1 No 0