NTSR2

GENE INFORMATION

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Gene name

NTSR2 (HGNC Symbol)

Synonyms

NTR2

Description

Neurotensin receptor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

11658178 - 11670164

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169006 (version 78.38)

Entrez gene

23620

UniProt

O95665 (UniProt - Evidence at protein level)

neXtProt

NX_O95665

Antibodypedia

NTSR2 antibodies
 

PROTEIN VIEW

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NTSR2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NTSR2-001 ENSP00000303686
ENST00000306928
O95665
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