EFNA1

GENE INFORMATION

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Gene name

EFNA1 (HGNC Symbol)

Synonyms

ECKLG, EPLG1, LERK1, TNFAIP4

Description

Ephrin-A1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q22

Chromosome location (bp)

155127460 - 155134857

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169242 (version 78.38)

Entrez gene

1942

UniProt

P20827 (UniProt - Evidence at protein level)

neXtProt

NX_P20827

Antibodypedia

EFNA1 antibodies
 

PROTEIN VIEW

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EFNA1-001
 
EFNA1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EFNA1-001 ENSP00000357392
ENST00000368407
P20827
Show all »
Show » Show » 205 23.8 Yes 0
EFNA1-002 ENSP00000357391
ENST00000368406
P20827
Show all »
Show » Show » 183 21.2 Yes 0