NR0B1

GENE INFORMATION

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Gene name

NR0B1 (HGNC Symbol)

Synonyms

AHC, AHCH, DAX1, DSS, NR0B1

Description

Nuclear receptor subfamily 0, group B, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p21.2

Chromosome location (bp)

30304206 - 30309598

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169297 (version 78.38)

Entrez gene

190

UniProt

P51843 (UniProt - Evidence at protein level)

neXtProt

NX_P51843

Antibodypedia

NR0B1 antibodies
 

PROTEIN VIEW

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NR0B1-001
 
NR0B1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NR0B1-001 ENSP00000368253
ENST00000378970
P51843
Show all »
Show » Show » 470 51.7 No 0
NR0B1-002 ENSP00000368246
ENST00000378963
A6NNU8
Show all »
Show » Show » 105 11.8 No 0