HINT1

GENE INFORMATION

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Gene name

HINT1 (HGNC Symbol)

Synonyms

HINT, PKCI-1, PRKCNH1

Description

Histidine triad nucleotide binding protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]

Chromosome

5

Cytoband

q23.3

Chromosome location (bp)

131159027 - 131171735

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169567 (version 78.38)

Entrez gene

3094

UniProt

P49773 (UniProt - Evidence at protein level)

neXtProt

NX_P49773

Antibodypedia

HINT1 antibodies
 

PROTEIN VIEW

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HINT1-001
 
HINT1-003
 
HINT1-005
 
HINT1-006
 
HINT1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HINT1-001 ENSP00000304229
ENST00000304043
P49773
Show all »
Show » Show » 126 13.8 No 0
HINT1-003 ENSP00000426860
ENST00000506908
D6RE99
Show all »
Show » Show » 78 8.6 No 0
HINT1-005 ENSP00000427499
ENST00000508488
D6RD60
Show all »
Show » Show » 103 11.5 No 0
HINT1-006 ENSP00000422444
ENST00000513012
D6RC06
Show all »
Show » Show » 65 7.3 No 0
HINT1-010 ENSP00000430909
ENST00000520028
Show » 27 3 No 0