GP9

GENE INFORMATION

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Gene name

GP9 (HGNC Symbol)

Synonyms

CD42a, GPIX

Description

Glycoprotein IX (platelet) (HGNC Symbol)

Entrez gene summary

This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]

Chromosome

3

Cytoband

q21.3

Chromosome location (bp)

129060767 - 129062406

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169704 (version 78.38)

Entrez gene

2815

UniProt

P14770 (UniProt - Evidence at protein level)

neXtProt

NX_P14770

Antibodypedia

GP9 antibodies
 

PROTEIN VIEW

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GP9-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GP9-001 ENSP00000303942
ENST00000307395
P14770
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