YWHAG

GENE INFORMATION

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Gene name

YWHAG (HGNC Symbol)

Synonyms

PPP1R170

Description

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma (HGNC Symbol)

Entrez gene summary

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q11.23

Chromosome location (bp)

76326794 - 76359031

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170027 (version 78.38)

Entrez gene

7532

UniProt

P61981 (UniProt - Evidence at protein level)

neXtProt

NX_P61981

Antibodypedia

YWHAG antibodies
 

PROTEIN VIEW

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YWHAG-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

YWHAG-001 ENSP00000306330
ENST00000307630
P61981
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