HOXD12

GENE INFORMATION

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Gene name

HOXD12 (HGNC Symbol)

Synonyms

HOX4H

Description

Homeobox D12 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

176099730 - 176101193

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170178 (version 78.38)

Entrez gene

3238

UniProt

P35452 (UniProt - Evidence at transcript level)

neXtProt

NX_P35452

Antibodypedia

HOXD12 antibodies
 

PROTEIN VIEW

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HOXD12-001
 
HOXD12-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXD12-001 ENSP00000385586
ENST00000406506
P35452
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Show » Show » 270 29 No 0
HOXD12-002 ENSP00000385132
ENST00000404162
B5MCD3
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Show » Show » 246 25.2 No 0