CST5

GENE INFORMATION

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Gene name

CST5

Synonyms

Description

Cystatin D (HGNC Symbol)

Entrez gene summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

23875935 - 23879750

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170367 (version 78.38)

Entrez gene

1473

UniProt

P28325 (UniProt - Evidence at protein level)

neXtProt

NX_P28325

Antibodypedia

CST5 antibodies
 

PROTEIN VIEW

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CST5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CST5-001 ENSP00000307132
ENST00000304710
P28325
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