CST2

GENE INFORMATION

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Gene name

CST2

Synonyms

Description

Cystatin SA (HGNC Symbol)

Entrez gene summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

23823769 - 23826731

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170369 (version 78.38)

Entrez gene

1470

UniProt

P09228 (UniProt - Evidence at protein level)

neXtProt

NX_P09228

Antibodypedia

CST2 antibodies
 

PROTEIN VIEW

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CST2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CST2-001 ENSP00000307540
ENST00000304725
P09228
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