CST1

GENE INFORMATION

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Gene name

CST1

Synonyms

Description

Cystatin SN (HGNC Symbol)

Entrez gene summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

23747553 - 23751268

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170373 (version 78.38)

Entrez gene

1469

UniProt

P01037 (UniProt - Evidence at protein level)

neXtProt

NX_P01037

Antibodypedia

CST1 antibodies
 

PROTEIN VIEW

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CST1-001
 
CST1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CST1-001 ENSP00000305731
ENST00000304749
P01037
Show all »
Show » Show » 141 16.4 Yes 0
CST1-002 ENSP00000381439
ENST00000398402
P01037
Show all »
Show » Show » 141 16.4 Yes 0