NETO2

GENE INFORMATION

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Gene name

NETO2 (HGNC Symbol)

Synonyms

FLJ10430, NEOT2

Description

Neuropilin (NRP) and tolloid (TLL)-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Chromosome

16

Cytoband

q12.1

Chromosome location (bp)

47077703 - 47143997

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171208 (version 78.38)

Entrez gene

81831

UniProt

Q8NC67 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NC67

Antibodypedia

NETO2 antibodies
 

PROTEIN VIEW

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NETO2-001
 
NETO2-002
 
NETO2-003
 
NETO2-004
 
NETO2-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NETO2-001 ENSP00000455169
ENST00000562435
Q8NC67
Show all »
Show » Show » 525 59.4 Yes 1
NETO2-002 ENSP00000306726
ENST00000303155
Q8NC67
Show all »
Show » Show » 518 58.7 Yes 1
NETO2-003 ENSP00000454213
ENST00000562559
Show » 365 41.4 No 1
NETO2-004 ENSP00000456818
ENST00000563078
Show » 194 21.6 No 1
NETO2-005 ENSP00000457133
ENST00000564667
Show » 228 25.6 No 1