KRT13

GENE INFORMATION

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Gene name

KRT13 (HGNC Symbol)

Synonyms

CK13, K13, MGC161462, MGC3781

Description

Keratin 13 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

41500981 - 41505705

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171401 (version 78.38)

Entrez gene

3860

UniProt

P13646 (UniProt - Evidence at protein level)

neXtProt

NX_P13646

Antibodypedia

KRT13 antibodies
 

PROTEIN VIEW

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KRT13-001
 
KRT13-002
 
KRT13-005
 
KRT13-007
 
KRT13-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT13-001 ENSP00000246635
ENST00000246635
P13646
Show all »
Show » Show » 458 49.6 No 0
KRT13-002 ENSP00000336604
ENST00000336861
P13646
Show all »
Show » Show » 420 45.9 No 0
KRT13-005 ENSP00000468221
ENST00000587544
K7ERE3
Show all »
Show » Show » 415 45.3 No 0
KRT13-007 ENSP00000466465
ENST00000590425
K7EMD9
Show all »
Show » Show » 165 19.2 No 0
KRT13-008 ENSP00000467833
ENST00000587435
K7EQH6
Show all »
Show » Show » 162 16 No 0