XAGE3

GENE INFORMATION

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Gene name

XAGE3 (HGNC Symbol)

Synonyms

CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3

Description

X antigen family, member 3 (HGNC Symbol)

Entrez gene summary

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p11.22

Chromosome location (bp)

52862525 - 52868068

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171402 (version 78.38)

Entrez gene

170626

UniProt

Q8WTP9 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WTP9

Antibodypedia

XAGE3 antibodies
 

PROTEIN VIEW

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XAGE3-001
 
XAGE3-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

XAGE3-001 ENSP00000303061
ENST00000346279
Q8WTP9
Show all »
Show » Show » 111 12.3 No 0
XAGE3-002 ENSP00000364640
ENST00000375491
Q8WTP9
Show all »
Show » Show » 111 12.3 No 0