MCC

GENE INFORMATION

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Gene name

MCC

Synonyms

Description

Mutated in colorectal cancers (HGNC Symbol)

Entrez gene summary

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q22.2

Chromosome location (bp)

113022099 - 113488830

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171444 (version 78.38)

Entrez gene

4163

UniProt

P23508 (UniProt - Evidence at protein level)

neXtProt

NX_P23508

Antibodypedia

MCC antibodies
 

PROTEIN VIEW

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MCC-001
 
MCC-003
 
MCC-009
 
MCC-011
 
MCC-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MCC-001 ENSP00000305617
ENST00000302475
P23508
Show all »
Show » Show » 829 93 No 0
MCC-003 ENSP00000386227
ENST00000408903
P23508
Show all »
Show » Show » 1019 113.3 No 0
MCC-009 ENSP00000485220
ENST00000514701
Show » Show » 715 79.9 No 0
MCC-011 ENSP00000421615
ENST00000515367
D6REY2
Show all »
Show » Show » 766 86.1 No 0
MCC-012 ENSP00000485492
ENST00000624689
Show » 169 19.1 No 0