HOXC5

GENE INFORMATION

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Gene name

HOXC5 (HGNC Symbol)

Synonyms

HOX3, HOX3D

Description

Homeobox C5 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

54032853 - 54035358

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172789 (version 78.38)

Entrez gene

3222

UniProt

Q00444 (UniProt - Inferred from homology)

neXtProt

NX_Q00444

Antibodypedia

HOXC5 antibodies
 

PROTEIN VIEW

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HOXC5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXC5-001 ENSP00000309336
ENST00000312492
Q00444
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