SP3

GENE INFORMATION

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Gene name

SP3 (HGNC Symbol)

Synonyms

SPR-2

Description

Sp3 transcription factor (HGNC Symbol)

Entrez gene summary

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

173906459 - 173965702

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172845 (version 78.38)

Entrez gene

6670

UniProt

Q02447 (UniProt - Evidence at protein level)

neXtProt

NX_Q02447

Antibodypedia

SP3 antibodies
 

PROTEIN VIEW

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SP3-001
 
SP3-002
 
SP3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SP3-001 ENSP00000310301
ENST00000310015
Q02447
Show all »
Show » Show » 781 81.9 No 0
SP3-002 ENSP00000413665
ENST00000416195
Q68DP2
Show all »
Show » Show » 738 77.9 No 0
SP3-003 ENSP00000406140
ENST00000418194
H0Y6K5
Show all »
Show » Show » 713 75.3 No 0