KRT2

GENE INFORMATION

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Gene name

KRT2 (HGNC Symbol)

Synonyms

KRT2A, KRTE

Description

Keratin 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

52644558 - 52652164

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172867 (version 78.38)

Entrez gene

3849

UniProt

P35908 (UniProt - Evidence at protein level)

neXtProt

NX_P35908

Antibodypedia

KRT2 antibodies
 

PROTEIN VIEW

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KRT2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT2-001 ENSP00000310861
ENST00000309680
P35908
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